Chiefs vs Colts – Game Preview (November 24, 2025, Arrowhead Stadium)

Team Form & Season Overview

• Kansas City Chiefs

  • The 2025 season has been inconsistent for the Chiefs, holding a 5–5 record midway through the season.

  • Offensively, they average around 26.6 points per game, while the defense allows roughly 17.7 points per game.

  • Key offensive players include Patrick Mahomes, running backs Isiah Pacheco, Kareem Hunt, and rookie Brashard Smith.

  • Defensively, the Chiefs rely on players like George Karlaftis, a standout pass rusher, to pressure opponents.

• Indianapolis Colts

  • The Colts have been stronger this season, with a 8–2 record.

  • Their quarterback room includes Daniel Jones, Riley Leonard, and Anthony Richardson, with Jones expected to start.

  • Star running back Jonathan Taylor is a major offensive weapon, recently breaking team rushing touchdown records.

  • On defense, key contributors include Mekhi Blackmon (CB) and Laiatu Latu (DL), providing stability and playmaking ability.

Head-to-Head History

• The teams have met 29 times historically. The Colts lead the series with 19 wins, while the Chiefs have 10.

• On average, the Colts score 22.5 points per game against the Chiefs, while Kansas City scores 20.6 points.

• Recent seasons suggest a slight edge for the Colts in matchups, although home-field advantage can shift dynamics.

Projected Lineups (Probable)

• Kansas City Chiefs:

  • QB: Patrick Mahomes

  • RB: Isiah Pacheco, Kareem Hunt, Brashard Smith (rotation)

  • WR: Hollywood Brown, JuJu Smith-Schuster, Xavier Worthy, Jason Brownlee

  • TE: Travis Kelce, Noah Gray

  • O-Line: Creed Humphrey, Jawaan Taylor, Josh Simmons, Trey Smith, others

  • Defensive Standouts: George Karlaftis (DL), plus regular starters in secondary and linebacker corps

• Indianapolis Colts:

  • QB: Daniel Jones

  • RB: Jonathan Taylor, Tyler Goodson, D.J. Giddens

  • WR: Michael Pittman Jr., Alec Pierce, Josh Downs

  • TE: Mo Alie-Cox, Will Mallory

  • O-Line: Quenton Nelson, Braden Smith, Matt Goncalves, Luke Tenuta, others

  • Defensive Standouts: Laiatu Latu (DL), Zaire Franklin (LB), Mekhi Blackmon (CB)

Game Analysis & Key Factors

• Home-Field Advantage: Arrowhead Stadium is a significant edge for the Chiefs. The loud crowd and familiar environment can disrupt the Colts’ offensive rhythm.

• Chiefs’ Challenges: With a 5–5 record, this is a must-win to keep playoff hopes alive. Any inconsistency could be exploited by Indianapolis.

• Colts’ Strengths: Jonathan Taylor’s rushing, combined with Daniel Jones’ passing versatility, will challenge Kansas City’s defensive schemes.

• Likely Scenario: This could be a tactical, close contest. If the Chiefs maximize home advantage and Mahomes connects effectively with Kelce, they could take the win. Conversely, disciplined play by the Colts, especially ball control and limiting turnovers, could see them leave Arrowhead with a victory.